Surgical Knee Denervation: The Future of Knee Pain Treatment

Are you suffering from chronic knee pain that hasn't responded to traditional treatments? A groundbreaking new Surgical Knee Denervation Procedure offers lasting relief by targeting the nerves responsible for transmitting pain signals from the knee joint.

What is Knee Denervation?

Knee denervation is a minimally invasive surgical procedure designed to alleviate chronic knee pain by selectively disabling pain-transmitting nerves around the knee joint. This advanced technique provides a viable solution for patients who have exhausted other treatment options, including medications, physical therapy, and even prior surgeries.

Benefits of Knee Denervation:

✔ Minimally Invasive – Faster recovery and reduced risk compared to traditional knee surgeries.

✔ Long-Lasting Pain Relief – Effectively reduces chronic knee pain by targeting specific nerve pathways.

✔ Preserves Mobility – Unlike joint replacement, this procedure maintains the knee’s natural function.

✔ Ideal for Various Conditions – Suitable for osteoarthritis, post-surgical pain, and nerve-related knee discomfort.

Who is a Candidate?

This procedure is ideal for individuals suffering from:

• Chronic knee pain unresponsive to conservative treatments

• Osteoarthritis or post-surgical knee pain

• Patients seeking alternatives to knee replacement surgery

• Non-arthroplasty candidates including those deemed at-risk for knee replacement

• Patient with residual pain after knee arthroplasty

Knee Treatment Research Group Opinion

Surgical knee denervation offers the most advanced, minimally-invasive knee surgery available today. This procedure is ideal for patients who have failed conservative management with injections and/or therapy, but are not candidates or do not desire a traditional knee replacement. Patients who have elevated risk with knee replacement may utilize denervation to provide long-lasting pain relief. This includes patients with advanced age greater than 75 years, elevated hemoglobin A1C higher than 7.0, and body mass index higher than 40. Patients who have pain after a knee replacement also benefit from this procedure.

Surgical denervation provides long-lasting pain relief with less risk than a knee replacement with the benefit of maintaining natural knee function. This procedure targets the nerve function, similar to a geniculate artery embolization and a radiofrequency ablation, but provides long-term pain relief as compared to the short-term pain relief with embolization and ablation.

If you have been told you need a knee replacement but feel your risk is elevated a surgical knee denervation may be ideal for you. Additionally, if you have had a knee replacement and still have pain a denervation procedure can help reduce your long-term pain. Around 20% of patients with a knee replacement are not satisfied with their surgery. If this is you a knee denervation can help you reduce your pain and increase your function.

Scientific Evidence

Hustedt et al. published a two-year outcome study of surgical knee denervation in 2024. They showed long lasting pain relief in 24 patients with pain reduction scores from 8.8 to 2.7, with associated improvements in functional and quality of life patient reported outcome scores.